Which of the following is NOT a risk factor for ICU delirium?

Which of the following is NOT a risk factor for ICU delirium?

• A. Sedation
• B. Immobility
• C. Infection
• D. Adequate sleep

Answer: (D)

Delirium in the ICU is driven by factors that disrupt brain function and the sleep–wake cycle. Sedation can push the brain into a more depressed state and mask or precipitate delirium by altering neurotransmitter balance. Immobility reduces sensory input and engagement, which can contribute to cognitive decline and delirium risk. Infection sparks systemic inflammation and cytokine release that can affect brain activity and clarity of thought. Adequate sleep, on the other hand, supports normal brain function, preserves circadian rhythm, and helps reduce inflammatory stress, making it protective rather than a risk factor. So the option that is not a risk factor is adequate sleep.

Delirium in the ICU is driven by factors that disrupt brain function and the sleep–wake cycle. Sedation can push the brain into a more depressed state and mask or precipitate delirium by altering neurotransmitter balance. Immobility reduces sensory input and engagement, which can contribute to cognitive decline and delirium risk. Infection sparks systemic inflammation and cytokine release that can affect brain activity and clarity of thought. Adequate sleep, on the other hand, supports normal brain function, preserves circadian rhythm, and helps reduce inflammatory stress, making it protective rather than a risk factor. So the option that is not a risk factor is adequate sleep.